It’s believed that the status of our health in later life is associated with the first bacteria that colonize our gut. In a prospective, longitudinal cohort study, Bittinger et al (2020), investigated the gut microbiome, proteome and metabolome in 88 African American newborn infants during the first month of life. Infants included in this study were full term infants (>37 weeks gestation) and did not have any major congenital abnormalities. Findings from this study showed that:
Keywords: Microbiota, Mode of delivery, bacterial DNA, metabolite, gut metabolome reprogramming
Bittinger, K., Zhao, C., Li, Y., Ford, E., Friedman, E. S., Ni, J., Kulkarni, C. V., Cai, J., Tian, Y., Liu, Q., Patterson, A. D., Sarkar, D., Chan, S., Maranas, C., Saha-Shah, A., Lund, P., Garcia, B. A., Mattei, L. M., Gerber, J. S., Elovitz, M. A., … Wu, G. D. (2020). Bacterial colonization reprograms the neonatal gut metabolome. Nature microbiology, 5(6), 838–847. Click here.
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